
When innovation is personal, technology doesn’t just scale—it saves lives.
For Melissa Mulholland, AI isn’t just a business strategy—it’s a lifeline. As CEO of Crayon and a former Microsoft executive, Melissa is scaling the power of AI across industries, driven by her own powerful experience with how technology can transform healthcare and human connection.
Melissa’s journey took a dramatic turn when she was told that her unborn son had posterior urethral valves (PUV)—a rare, life-threatening condition. Determined to give him a chance, she underwent a high-risk medical procedure that saved his life. That experience became a catalyst for her mission: to make life-changing technology accessible to all.
At Microsoft, Melissa began championing AI in healthcare, sharing her story with global health leaders to inspire action. One of those conversations sparked a collaboration between Crayon and Oslo University Hospital, where AI now supports colon cancer screening and patient monitoring—real solutions with life-saving potential.
“My story demonstrates the transformative impact of AI in healthcare, driven by personal experiences and innovative technology.” — Melissa Mulholland
Now leading Crayon, Melissa continues scaling inclusive, purpose-driven innovation across the globe. She’s helping expand access to AI for underserved communities, breaking down geographic and economic barriers in healthcare, and ensuring technology is easy to use, easy to understand, and accessible to everyone. Closer to home, she sees AI’s power daily—her son Conor uses speech therapy apps powered by AI to build communication skills and confidence.
Melissa’s work proves that meaningful innovation must be both scalable and personal. By connecting human needs with technological possibilities, she’s building a future where AI doesn’t just solve problems—it delivers hope.
About #empowHER50 campaign
This campaign celebrates women leaders at Microsoft, past and present, who have been instrumental in democratizing access to technology, opportunity, and growth. By honoring their contributions over the last half-century, this campaign highlights stories of resilience, innovation, and inclusivity. Through digital spotlights, a commemorative coffee table book, live recognition events, and more, the campaign inspires collective action toward achieving equitable societal goals. To learn more about empowHER50, please visit https://womenincloud.com/empowHER50
To learn about Microsoft 50th celebrations: https://news.microsoft.com/microsoft-50/